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    Faculty Profile — Is this you? Login to edit.Last Modified Time: 04:01:08 PM Wed, 23 Oct 2013 
Image of  Raimund J. Ober
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Raimund J. Ober
Professor-Electrical Engineering
Office MailstopRoom No.: ECSN 2.524 
Email Address  Raimund.Ober@utdallas.edu    Primary Phone Number 972-883-2158    URL Faculty Homepage    Media Contact
 Professional Preparation
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 DegreeMajorInstitutionYear
 Ph.D.Electrical EngineeringCambridge University1987
 M.Phil.Operations Research and Control EngineeringCambridge University1985
 CertificateAdvanced Study in MathematicsCambridge University1984
 VordiplomMathematikTuebingen University1982
 ZwischenpruefungPhysikTuebingen University1982
Collapse Section Expand Section Research and Expertise
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Research Interests

My research interests involve the development and use of bionanotechnology approaches to the study of biological problems. In particular, my lab works on experimental and image processing approaches to fluorescence microscopy with a specific emphasis on the detection of single molecules. The work on biosensors concerns development of improved experimental and data analysis approaches for the study protein-protein interactions. The biological questions being studied, in collaboration with Prof. E.S. Ward at UT Southwestern Medical Center at Dallas, deal with immunological problems as the question of how the dynamics, transport and distribution of antibodies are regulated in vivo. To this end, for example, the trafficking of antibody molecules is imaged by fluorescence microscopy in a live cell environment.

The engineering aspects of the research involve the development of advanced analytical tools, software and instrumentation. Recently, my group has investigated the accuracy with which important parameters can be determined from experiments using information theoretic methods.

Collapse Section Expand Section Publications
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  YearPublication  Type
N/A
S. Ram, P. Prabhat, J. Chao, E.S. Ward, and R.J. Ober. High resolution 3D single molecule tracking reveals complex endocytic pathways in cells, submitted.
Category: National Academy of Sciences
Conference paper
2013
Gan, Z., Ram, S., Ober, R. J., Ward, E. S. Using Multifocal Plane Microscopy to Reveal Novel Trafficking Processes on the Recycling Pathway. Journal of Cell Science, (126)5: 1176-1188, 2013.
Other
2013
Chao, J., Ram, S., Ward, E. S., Ober, R. J. Ultrahigh accuracy imaging modality for super-localization microscopy. Nature Methods, 10(4): 335-338, 2013.
Other
2013
Bansal, P., Khan, T., Bussmeyer, U., Challa, D.K., Swiercz, R., Velmurugan, R., Ober, R.J., Ward, E.S. The encephalitogenic, human myelin oligodendrocyte glycoprotein-induced antibody repertoire is directed toward multiple epitopes in C57BL/6 mice. Journal of Immunology, accepted, 2013.
Other
2013
Chao, J., Ram, S., Ward, E. S., Ober, R. J. Two approximations for the geometric model of signal amplification in an electron-multiplying charge-coupled device detector. SPIE International Symposium on Biomedical and Optics (BiOs), 858905-858905-7, 2013.
Other
Collapse Section Expand Section Presentations and Projects
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  1  
Start DateEnd DatePresentation/Project
10/22/2004 10/22/2004 Problems in Fluorescence Microscopy Image Analysis: Localization of Single Molecules and Point Spread Function Estimation
22 October 2004, Imperial College London. Title: Problems in Fluorescence Microscopy Image Analysis: Localization of Single Molecules and Point Spread Function Estimation.
10/20/2004 10/20/2004 Imaging Single Molecules in Live Cells
20 October 2004, Engineering Department, Cambridge University. Title: Imaging Single Molecules in Live Cells.
09/24/2004 09/24/2004 Problems in Fluorescence Microscopy Image Analysis: Localization of Single Molecules and Point Spread Function Estimation
24 September 2004, Oklahoma Medical Research Foundation. Title: Problems in Fluorescence Microscopy Image Analysis: Localization of Single Molecules and Point Spread Function Estimation.
03/08/2004 03/08/2004 Problems in Fluorescence Microscopy Image Analysis; Accuracy of Single Molecule Localization and Estimation of Point Spread Functions
8 March 2004, National Institutes of Health, Bethesda, MD. Title: Problems in Fluorescence Microscopy Image Analysis; Accuracy of Single Molecule Localization and Estimation of Point Spread Functions.
01/26/2005 01/26/2005 Three-dimensional state space realization algorithm: noise suppression of fluorescence microscopy images and point spread function estimation
26 January 2005, Photonics West, San Jose, CA. Title: Three-dimensional state space realization algorithm: noise suppression of fluorescence microscopy images and point spread function estimation.
Collapse Section Expand Section Appointments
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DurationRankDepartment / SchoolCollege / OfficeUniversity / Company
2006-PresentFacultyDepartment of Bioengineering The University of Texas at Dallas
2005-PresentMemberGraduate Program in Biomedical Engineering The University of Texas at Dallas
2005-PresentMemberGraduate Program in Biomedical Engineering The University of Texas at Dallas
1999-PresentProfessorDepartment of Electrical Engineering The University of Texas at Dallas
1997-1998ProfessorMathematical Sciences The University of Texas at Dallas
1996-1996Adjunct Faculty  University of Texas Southwestern Medical Center
1993-1997Associate ProfessorMathematical Sciences The University of Texas at Dallas
1990-1993Assistant ProfessorMathematical Sciences The University of Texas at Dallas
1987-1990Research FellowDepartment of Engineering Cambridge University
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 Additional Information
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Senior Member IEEE

Honors and Awards
  • Senior member, IEEE

Memberships
IEEE, SPIE, Biophysical Society, American Society for Cell Biology, Biophysical Society, Texas Faculty Association

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